Currents in zebrafish caudal fin regeneration

The team of Joaquín Rodríguez-León recently implicated, for the first time, a  specific channel in the cell membrane, called V-ATPase, in caudal fin regeneration of adult zebrafish. This channel pumps hydrogen ions (H+) out of the cells, thus generating an electrical current that aids correct tissue  regeneration. See the Plos one website and comment on Science daily.

A clock in limb patterning

Caroline Sheeba, Raquel Andrade and Isabel Palmeirim have recently published a featured perspective article in the Journal of Molecular Biology. In this article they present an integrated temporal and spatial model for limb patterning, proposing that the limb Clock may allow temporal information to be decoded into positional information when the distance between opposing signaling gradients is no longer sufficient to provide distinct cell fate specification. The authors were also invited to prepare a figure for the cover of the Journal of Molecular Biology! See the JMB website.

 

Drosophila axis elongation

 

Sérgio Simões, who did his PhD work in António Jacinto's lab, has recently published part of his postdoctoral work in New York in the Journal of Cell Biology. In this paper, the authors show that Rho GTPase and Shroom actin-binding protein have distinct roles in Rho-kinase localization and actomyosin contractility during Drosophila axis elongation. See the JCB webpage.

Like a purse string

   Wound closes like a purse string

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Trunk or Tail?

   How to stop a trunk and start a tail?

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