Jobs

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Lab manager position at CEDOC

Encontra-se aberto concurso para a atribuição de uma Bolsa de Investigação para Mestre com a referência DAI/2017/23 no âmbito do projeto EMBO - IG Project Number 3311, com o título (Temporal and Metabolic Regulation of stem cells), na instituição Centro de Estudos de Doenças Crónicas da Faculdade de Ciências Médicas da Universidade Nova de Lisboa, financiado pelo EMBO - European Molecular Biology Organization. O concurso encontra-se aberto de 04 de Julho a 17 de Julho de 2017. Mais informação aqui.
 

 
PhD Candidate or PostDoc, Boxem group, Utrecht University, The Netherlands

We are seeking to recruit two enthusiastic and motivated PhD students and/or Postdoctoral fellows, to join the group of Dr. Mike Boxem at Utrecht University. The candidates will investigate the control of epithelial polarity in the nematode C. elegans as part of the Vici project “Deciphering the systems that control epithelial cell polarity”, funded by the Netherlands Organisation for Scientific Research (NWO).

Project summary
The ability to generate an axis of polarity is a fundamental property of animal cells, and loss of cell polarity contributes to diseases including cancer. The research in this Vici project focuses on two questions: i) what is the network of interactions between polarity determinants
that maintains polarity in established epithelia, and ii) what are the direct consequences of disrupting cell polarity on epithelial integrity, morphology, and cell fate.
To address these questions, the candidate will combine precisely controlled perturbations of the polarizing system in C. elegans epithelial with accurate characterization of the effects of these perturbations on the polarizing machinery and on epithelial organization and cell fate.

About the organisation
The research of the Developmental Biology division focuses on studying biological principles in the context of living, developing multicellular organisms. Three research groups use C.elegans as a model system, providing critical mass and a vibrant atmosphere with many national and international contacts.

Offer and application procedure
The candidate is offered a full-time position for 4 years (PhD) or 3 years (Postdoc). Please submit your application by e-mail to Dr. Mike Boxem, This email address is being protected from spambots. You need JavaScript enabled to view it. . Attach a letter of motivation detailing research interests and experience, Curriculum Vitae and (email) addresses of two referees. For details, please visit https://goo.gl/BVqoLk.


Amoyel lab is recruiting Phd students and Postdocs

 
The Amoyel lab is funded by the Medical Research Council to study how stem cells compete with each other to remain in the niche. We use the Drosophila testis as a model to study how signalling differences confer a competitive advantage to one stem cell over its neighbours. We combine powerful fly genetic approaches with single cell labelling methods to track single stem cells over time, both in live and in fixed tissue, and understand their behaviour. For more information please visit our website: http://www.amoyellab.com/ or contact Marc Amoyel by email:  This email address is being protected from spambots. You need JavaScript enabled to view it. .uk
 

Post-doctoral positions opening in Pierre Léopold’s lab, Institut Curie - Paris – France

The lab of P. Léopold is moving to the Curie Institute in Paris and offers postdoctoral positions to explore the physiology of organ growth and size determination.
An important aspect of body size determination is the coordination of growth arrest among organs and its coupling with the program of development. Our current projects aim at understanding this coordination and its integration with environmental conditions such as nutrition. For this, we make use of genetics and physiology on the Drosophila model to explore multiples aspects of interorgan communication. More information on the Leopold lab can be found at: http://ibv.unice.fr/EN/equipe/leopold.php.

The applicants must have a solid background in developmental biology and possibly strong expertise in fly genetics. Fellowships are funded by an ERC advanced grant and are for 3 years. Applications including a CV and the name of 3 referees should be sent to P. Léopold ( This email address is being protected from spambots. You need JavaScript enabled to view it. ).


Postdoctoral Position - Vascular Morphogenesis Lab

The Vascular Morphogenesis Lab is recruiting highly motivated postdoctoral fellows under the project AXIAL.EC (id:679368), funded by the European Research Council (ERC). Candidates should contact Claudio Franco at This email address is being protected from spambots. You need JavaScript enabled to view it.


Research Focus

The formation of a functional patterned vascular network is essential for development, tissue growth and organ physiology. Several human vascular disorders arise from the mis-patterning of blood vessels, such as arteriovenous malformations, aneurysms and diabetic retinopathy. Although blood flow is recognised as a stimulus for vascular patterning, very little is known about the molecular mechanisms that regulate endothelial cell behaviour in response to flow and promote vascular patterning. Projects are on the following topics:
– Endothelial cell biology in development and disease (cancer; AVMs; ischemic disease);
– Coordination of cell migration and cell polarity;
– Novel regulators of flow-dependent endothelial cell polarisation.

The Vascular Morphogenesis Lab is located at the Instituto de Medicina Molecular (iMM) at the heart of Lisbon. iMM has a young, multidisciplinary and vibrant international research environment. iMM hosts 9 ERC grantees, 2 Howard Hughes Medical Institute Scholars, 3 EMBO Young Investigators and 1 Bill and Melinda Gates Foundation grantee.


Postdoctoral Position in Transcriptional Control of Craniofacial Morphogenesis / Systems Biology

Positions for highly motivated postdocs are available in Dr. Licia Selleri’s laboratory in the Program of Craniofacial Biology & Institute of Human Genetics of the University of California, San Francisco. The laboratory has used the mouse as a model system to study the transcriptional control of morphogenesis in developmental processes, with a special focus on organogenesis of the craniofacial & appendicular  skeleton and spleen.

The projects for the available positions will be aimed at understanding the cellular, genetic, and regulatory mechanisms underlying midface morphogenesis in vertebrate embryos. To this end, we use genome wide, systems biology approaches and in vivo imaging, leveraging the strengths of different animal model systems, including mouse, rat, jerboa, chick, and human embryos.
Candidates must hold a PhD degree (or equivalent) in molecular biology, biochemistry, genetics, or relevant field. The ideal candidate should also have some bioinformatics skills and strong interests in gene regulation or protein interactions in morphogenesis. Our lab is located within the stimulating scientific environment of UCSF on the Parnassus Campus. Additionally, the UC system recently adjusted its compensation guidelines to provide highly competitive postdoc salary.
Qualified applicants should send their CV, a brief description (less than 1 page) of a potential research project to conduct during their postdoc, and contacts of three referees to This email address is being protected from spambots. You need JavaScript enabled to view it.


 

Head of Flow Cytometry Shared Resource Lab, Instituto Gulbenkian de Ciência, PT.

The Instituto Gulbenkian de Ciência (IGC) is a research institute devoted to biological and biomedical research and to graduate training. Our main assets are excellence, originality, communication and cooperation. Those are the basis for facilities and independent research groups to work in an environment which encourages interactions and exploits synergies with minimal hierarchical structure. The scientific programme of the IGC is multidisciplinary, including Cell and Developmental Biology, Evolutionary Biology, Immunology, Host-Pathogen Interactions, Disease Genetics, Plant Biology, Neurosciences, Theoretical and Computational Biology.

We are currently seeking for a Head for our Flow Cytometry Shared Resource Lab. The candidate should have the following profile:

. Minimum 3 years of experience on providing services in the context of a flow cytometry core facility
. Have developed or had been deeply involved in research projects using flow cytometry extensively
. Ability to troubleshoot both analysers and cell sorters (including non BD machines)
. Strong technical skills
. Willingness to get involved in ongoing research projects
. Ability to organize and maintain detailed documentation
. Involved on international networking and ability to represent the Institute concerning issues in flow cytometry
. High level of written and spoken English
. Strong communication skills, positive attitude and capable to work in a team
. Highly motivated, ethic, creative, dedicated, eager to learn, and devoted to project goals

The candidate will have the opportunity to work in a dynamic and interdisciplinary environment and to develop her/his skills. The IGC has an excellent track record of launching highly qualified technicians and service heads, by providing the right environment to learn and develop international level careers. The selected candidate will have the freedom to apply to technical research grants and scientific grants together with research groups. As such, PhD holders are preferred.

Salary will be adjusted to the level of experience of the candidate.

A CV, motivation letter and up to 3 references should be sent to This email address is being protected from spambots. You need JavaScript enabled to view it. with the subject: Flow Cytometry Head.

Further questions can be addressed to Nuno Moreno ( This email address is being protected from spambots. You need JavaScript enabled to view it. )


 

Available Postdoctoral Position

A fully funded postdoctoral position is available to work on pre-­mRNA splicing during Drosophila early embryonic development. More information here.


 

Three positions available in UK:

- 3 year postdoctoral post in Becker group (Edinburgh)

- Reader/Associate Prof in Biomedical Genetics (Bath)

 

Funded Ph.D. Position, Cell division and morphogenesis

Our team addresses emerging questions in the field of cell and tissue dynamics (website). A Ph.D. funded-position is opened to explore the mechanisms of cell division during Drosophila epithelial tissue morphogenesis using state-of-the art imaging methods, genetics and quantitative approaches in the context of the PolarNet Marie Curie Initial Training Networks (http://polarnet-itn.eu/). Our team is part of the Curie Institute. The Curie Institute is an ideal and challenging environment for any candidate who is deeply interested in cell and developmental biology research. The Institute has state-of-the-art core facilities for microscopy, protein purification and mass spectrometry. In addition, the Curie Institute is ideally located in the centre of Paris and, with a large international community of students and scientists, it provides a wonderful environment for foreign students.
Questions regarding the projects and applications should be addressed by email to: This email address is being protected from spambots. You need JavaScript enabled to view it.



4‐year PhD position, Casares lab, CABD (Sevilla)

Organ Size Control: gene regulatory networks and tissue mechanics

We are looking for candidates with a master degree (or close to completing it) in Biophysics, Physics, Biology, Biotechnology and related areas. If you are interested, send an email to Fernando Casares: This email address is being protected from spambots. You need JavaScript enabled to view it.

More info here.



PhDs available in Developmental Biology

There are two BBSRC DTP PhDs in Developmental Biology  available in the Grant Wheeler and Andrea Munsterberg labs for UK and EU students.
 
Links to the two PhDs are here:

Postdoctoral position with Jerôme Gros at the Institut Pasteur, Paris, France

We invite applications for a postdoctoral research fellow to join the lab of “Imaging and Regulation of Morphogenesis in Higher Vertebrates” at the Pasteur Institute in Paris, France. Our lab is interested in understanding morphogenesis of developing structures, at a cellular level. Using avian models we combine state-of-the-art live imaging microscopy, quantitative analyses, biophysical, cellular and molecular biology approaches to access the cellular dynamics of development.
 
This specific project aims at elucidating the cellular events underlying the initiation of limb bud formation and how such cell events are dynamically regulated at the molecular level, using the generation of transgenic avian lines.
 
The position is a 4-year postdoctoral position funded by the ERC (European Research Council), available immediately. We are seeking highly motivated candidates with expertise in developmental and/or cellular biology. Experience in imaging and chick development will be positively considered.
 
Applicants should send a cover letter (describing briefly research interests), a C.V and contact information for up to 3 academic references to This email address is being protected from spambots. You need JavaScript enabled to view it. .
 
More info here.

 

Post-doctoral position available at the CBI Toulouse ERC funding, 3 years

http://cbi-toulouse.fr/eng/equipe-suzanne

Apoptosis is a cellular process essential to eliminate potentially harmful cells, but also to sculpt tissues during morphogenetic events. By following apoptosis in living tissue during an apoptosis-dependent morphogenetic event (Drosophila developing leg folding), we unraveled recently that apoptotic cells produce a pulling force upon the apical surface of the epithelium thanks to a Myosin II cable specific of apoptotic cells (Monier et al, 2015, Nature). This work reveals that apoptotic cells actively influence their surroundings and trigger tissue remodeling. This discovery leads us to ask if this apoptotic force conserved in vertebrates.
 
In order to answer these questions, we propose to compare apoptotic cell behavior in fly and mouse models and test the presence of an apoptotic force in mammalian cells and mouse neuroepithelium (in collaboration with Alice Davy, CBD, Toulouse). In parallel, it would be also interesting to test the effect of apoptosis in different tumor models.

Qualifications:
- Interest in cell biology
- Expertise in mouse development is required
- Expertise in imaging would be a plus
- Expertise in flies would be a plus

Highly motivated candidates should send to the following address This email address is being protected from spambots. You need JavaScript enabled to view it. a brief description of their research interests and career goals, their CV, and contact information for three references with their application.


 

Post-Doc - Sophie Jarriault Team

Reference : POST-DOC S.J.

We are looking for an outstanding scientist to help us solve open questions in the cellular  reprogramming field. We have pioneered the study of natural instances of cellular reprogramming establishing the worm as a unique model (see for ex. Jarriault, PNAS 2008; Richard, Dev. 2011; Kagias, PNAS 2012; Hadjuskova Genesis 2012; Zuryn Science 2014), while fostering a creative and enthousiastic working atmosphere in the lab. The project will focus on understanding the extrinsic events and intrinsic cellular properties that make some cells amenable to reprogramming. C. elegans has proved a powerful model to unravel conserved principles underlying how a cell can naturally change its identity. For more information about the group, please visit: http://igbmc.fr/jarriault

Our team is part of the Cell and Developmental Department, at the IGBMC, in Strasbourg, France. This Research Institute (www.igbmc.fr) provides access to state-of-the-art facilities and a vibrant international research environment.

The successful candidate should have a PhD (or be in the final stages of completion) and be highly motivated with a strong interest in Developmental and Stem Cells Biology. The ability to work both independently and as a team member and experience in the use of molecular biology and genetic techniques are essential. Experience in working with C. elegans is a plus. Note that a very good track record and at least one publication as a first author is required.

Applicants should email a cover letter, a CV, a description of research experience as well as the contact info for 2-3 references to: Sophie JARRIAULT   -   e-mail : This email address is being protected from spambots. You need JavaScript enabled to view it.



Yale Postdoc Position at Dr Simons Lab 

NIH-funded postdoctoral position available in Professor M. Simons laboratory to study lymphatic and blood vasculature development using mouse and/or zebrafish models. Laboratory interests include vascular fate specification, endothelial signaling, lymphatic vasculature and valves development and endothelial signal transduction. The successful candidate with have extensive experience in mouse/fish developmental biology techniques and working understanding of cell signaling.

Applications and/or inquiries should be sent to This email address is being protected from spambots. You need JavaScript enabled to view it.


Post-doc position: Cell division and tissue morphogenesis

Our team addresses emerging questions in the field of cell and tissue dynamics (http://ugbdd.curie.fr/en/article/00219-polarity-division-and-morphogenesis). A post-doctoral ERC funded-position is opened to explore the mechanisms of cell division during epithelial tissue morphogenesis using state-of the art imaging methods, genetics and quantitative approaches. Our team is part of the Curie Institute. The Curie Institute is an ideal and challenging environment for any candidate who is deeply interested in cell and developmental biology or interdisciplinary research. The Institute has state-of-the-art core facilities for microscopy, protein purification and mass spectrometry,... In addition, the Curie Institute is ideally located in the centre of Paris and, with a large international community of students and scientists, it provides a wonderful environment for foreign post-docs.
Questions regarding the projects and applications (curriculum vitae and contact information of 2 references) should be addressed by email to: This email address is being protected from spambots. You need JavaScript enabled to view it.


Postdoctoral position in the Institut Pasteur / Institut Imagine, Paris

The laboratory of S. Meilhac studiesy how cells are coordinated at the level of the tissue and how their local behaviour generates global changes of organ shape. We address these questions in the context of heart morphogenesis, using approaches of genetics, cell biology and computer modelling. Our work in the mouse is relevant to congenital heart defects in humans.

For more information on the laboratory go to http://www.pasteur.fr/en/research/developmental-stem-cell-biology/units-groups/heart-morphogenesis

We are always interested in hearing from students and post-doctoral candidates who are interested in joining our group. Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.